Non-invasive image-guided targeted drug delivery

Advances in Targeted Drug Delivery

Ultrasound-guided nanobubbles for targeted drug delivery

In a large number of biological and environmental applications, ultrasound (US)-powered microand nanomotors have attracted considerable attention. However, their applications in biological settings have been limited due to the incompatibility of metallic motors and the lack of precision guiding. Here, we demonstrate that cellulosic polymer nanobubbles (200-800nm) can be propelled, aligned, acce...

Advances in Targeted Drug Delivery

Effects of non-newtonian properties of blood flow on magnetic nanoparticle targeted drug delivery

Objective(s): One applications of nanotechnology is in the area of medicine which is called nanomedicine. Primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. An important issue in simulating the motion of nanoparticles is modeling blood flow as a Newtonian or non-Newtonian fluid. Sometimes blood flow is simulated ...

Self-regulating "smart carriers" for non-invasive and targeted drug delivery.

The skin of mammals is an excellent anatomical and biochemical barrier. Non-invasive transport across the skin is therefore only feasible for relatively small molecules (MW > 400 Da) [1]. Special tile-like cell organisation in the skin and the sealing of intercellular contacts by the lipids that are tightly packed and attached covalently to cutaneous cell membranes are both responsible for this...